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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef4509296807f8a78a43a74f3ddbaab47eaf5464dfd261573d166e3814e7696f' 
  AND token = 'RHq1UMg7o+674kK71yJ4TYP6pA2TNE9dlfDUKBGw3ZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}