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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f353ec5d60814182a2a8c1f88264ea3c36fdc29fbb26570a573c2a93555dce43' 
  AND token = 'ZA5ReSRSpz5Md3hWm7dRS9XIbWOUTrj3hJXhHYlIG/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}