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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78ca1540a32ac70927437e96a55007b9d278bdeea16c8717ac1f26e7e6487018' 
  AND token = 'ZxE+vb6qX2cOykzE9Rv8/mLtOwdhfFBPOrLAqPx5Q2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}