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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4dcc6125fc2506e6b69bb9d85cb6c76ff62b793c724ee724b060a6a2480541e' 
  AND token = 'OGQcYxUXhn+G7gdlagzHbiUAMQ8j2z5s2JD2CtD/R5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}