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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de018f94ca898050a2f05c2a0c62131b12ab25f1d3b91a56294cc321e5a9c28c' 
  AND token = 'loN8y8alRMg457RoVBpnAgh0iBSkWKf+fE69CRufcCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}