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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5282a55880f0f1f470a7c4c4225969900fbec80440c412446613afbe3ec6960c' 
  AND token = 'MHwUG8vGFAFd+5XI9Ci96xYL8cBg6g3skvmY0bH1Ku0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}