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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f28e261ad7455b4108267280dd705547abb5f296589f1954db5721f1de1e962b' 
  AND token = 'lI6Ej7H2YoN11RAoB1c7kOEXowCjZfKHuxLeXM5ddok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}