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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '404734e1e5db14289d3cd777ba7b0cc923efc4bf8e61002ff1dde908db2acf56' 
  AND token = 'ZYhAhtUjZD3RDUB+OUugx6eIOZ95dAkm1UG98XmChtw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}