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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21d6b171c73081470b63a1d56f28e4ec2edb03761672912d9bcc4c39129b424c' 
  AND token = 'Q2i2g+EqBMFiWHZD4jw6ycJLUBlDor+k5rWemyDkcZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}