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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '006e9cd6ca1fb86fe02f2fa1308c5481beaee696c5396efa5f80282f9e750249' 
  AND token = '9B+5/H1uLGNDDTRTW6cGNBkhAQnUI/h80Y4k3hTqMFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}