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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a715e9ecd0a3d621a20baa26e954ba96864dac3217f78708b1a8507fee8ce2f8' 
  AND token = 's1KK9DgWZ8j8FR8uRCChoCrY1gSMkenYAmdzYTCv44s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}