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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '073146e0dc65eed1499f45fddeabef357a70884236a1af1de21d073180d818bf' 
  AND token = 'NTJ+w3Ej/TWtD4i6w+A+AvuHG+qCh55NIaV/4jOk+u0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}