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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff614ec5c8c76595920823ddf9d0b05c2634151039f6817ede5cf230c22e4d03' 
  AND token = 'KVMvU1jb1EWW3PaVepc7stj8fXhhbnCXFe+9aW5jpVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}