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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee6ff4ef98fc932b8b9b894720c18e1abe877a33a7dd777cc9adf69f695cd0b7' 
  AND token = 'trWNnMt1LxWuARt+H/qy1aCqjY79GEyRhP6LzTkM93Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}