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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb0519ebf7f7f3470f60769968cc4e416786bd051e20d3517bf4cde39a11c544' 
  AND token = '8E0+7CvHQu4SEUero2jlPKheyttGdjF+4LI2zu4dU4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}