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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ca0c701b8f622ffa3c4e07d6455c21b3215bc3177935d32286fcbb6cf3bcbe2' 
  AND token = 'GfmcXwTp6WWByzmd+NA8lQwUL5VYECBQihhc7WZ0Mnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}