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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afce938a61401887ba4f53ff83f1657eddcc4832496598d5dc16c979c09642c4' 
  AND token = '37h0PHfio8ptojZOdPK8kLnsk0pGUXcopNGl73/iMT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}