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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49960c0984ef442d689cec1563c348430b1c3e8f8a9a9378aed0ea22c693891c' 
  AND token = 'yKt5SfHCKYg4MmM9E93b/wVFgdcH8dGExHR/lkmFZMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}