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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78f3b86ef5ad83f458205d46e20dd7824ae25f5877d058b8d0a92a4698c5cee2' 
  AND token = 'zM4JhHr9a6gC/ILcyacdgMp5Ew3JvNC5K8t4XjkzZgQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}