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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c79e9c83eed1f69b4e45c9997bd190d305a125ccd5e1cd16063a926df63f0493' 
  AND token = '3QivFoRMnc1rhdzZOroxgz5TsekUua0rvxtGTaaj7yE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}