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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdf58868eca8c1f456acf4e81d80b87f86afea9ba71c7d7ad2d0865455059330' 
  AND token = 'dp2F/spvEwSyy8LN4rYYs0P65qlVUxyPD1vfjLSWRso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}