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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16595606b5fcf9bd20cbb6bb7a1b5884eba944b9194a4eb5558f93c74ff7ef2a' 
  AND token = 'aShrbUTTZCai7gYV4jLKBsgmQa3BAaVXRnumTM4dcfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}