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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81e392d7597df544881d51c3dbe670e8331e1b278feb179a9367bff1661a5aa0' 
  AND token = 'tqLOaUcVR1tVIwBBay8t46BemIWvSVaEemyo9BMtPKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}