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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd194d883cd4e540cea7f3b354f872c013155492002c9f75fda4318080cb10a11' 
  AND token = 'dupwIGlkhfqV3srsrWGrnD9uchqtZ39zJnJAtxlH8DE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}