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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ce337a0d9e5683663eee6c70c225a0df3b49df2b136fd13101d25c11f17b551' 
  AND token = 'qMqmSaXCy/rWWDCMyly/n2pdfFGCxgj7mp7ezB2BcOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}