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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b46575b744ed7b0f2c274f6812ce6f0c1ebe539cc5907197482a019c82e1ebf' 
  AND token = 'TnPsM/xRKVCXl4jp2tJd7x0PFFbTF66iu7UPUjmCjxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}