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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd6baf159aa5a17f9a87c40d467d6a60010faa12b1e3f04d84284809026d5699' 
  AND token = '2VY0CUTV/4xqNAJHQVKOYpPwBcHlC9ZQaNJ0osqaC6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}