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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e8c65442653e47f2f0f05ccd1f547167547c90e2aa7ef6591503045e51bf812' 
  AND token = 'CR6vkw+eNqakQ+8ALAmX8rtIpKKjjz+oE4UKIlWwKIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}