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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '316109ce6d4d5b6d4a5a1c88036ab1b002b8c78ac8aa888d06b7dda747f44fd2' 
  AND token = '1qdMpzWoFGsBno8LgBk4YyGXL7ouCbrFq21oeycrFEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}