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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '174069174bb098551f934d975b7e94f4bf345f0fc29dce17f74da453e42f7145' 
  AND token = 'qYJbvqp4koLWoMWKmRIcsqy5k7IyWAUAd0UskvtDbrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}