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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b727f65001c9e484c82155894bf2ff7acb1cb9b9e6aa841b2c0168cd9856cae' 
  AND token = 'yy1RHw4LbYxwyHUqo6dbmJpn9iGY2wkXlLrwI7CBQkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}