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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cff1e49e0f57cc23e341aa2053ca1c748b0299822c9619c1f06eaee322b2d0c' 
  AND token = 'vawJj/wfd/qSlGYROe/iVXy5cqLiLIGC7kzMINRL7uU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}