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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd34b5f762c6f8a5a5044f10dbbff4358cb0429108e072331bf0615a4b0a4a44a' 
  AND token = 'oUKkvWBvvrqfHdotOBWCrJNEsLnnWy58CPnhYflhWUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}