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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1f5da1bf6e5a4bc4831870675f32ab2573ce7652d52f23bdce0e1505430e89c' 
  AND token = 'o9lFsOkTkRyQ3ZF+1vWqwVaVnonJFMox+TQbQr3j8LM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}