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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce2c80c40ed4da05b2a3fd3501387a915a88ca9c82f021cbe2e973240301ddc6' 
  AND token = 'AYrcZ86eZeXAZxQ+UQV0QaThPzeGTiD4LFp0tzaAOFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}