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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '353ed12c8d31511be30d01c4a887b36c4509eaa0993ec65462c66de94d3582ba' 
  AND token = 'cOErlznhgXxGa6ZHsUzbhZQ6ye1x1RBgHEMc3FX9Amw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}