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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a4fe46334b39b2f7d25540a1ac6d5fa87e3d2cadc7bc3de1d042f25242cb135' 
  AND token = 'xZRQNG0WQwNbFKe1ihqE41W3LBM1o9pElys/DWwk8Ik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}