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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a2b1721ec704b1c2a7f7f23b0720fdcd1363e74dbf42f5f3b9edb9dddffded8' 
  AND token = 'PbaChrAO+/5/nkGVe9DYJIv8VlhdlSg+E3bl7tGTFLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}