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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e12940e262d9bd044c4fc69d041b3dcb5092c602322b28406c4dfb121f550de' 
  AND token = 'R9Knhx7U51lMI9f16Zt7VvB3tk94lDVigaJRD7L8zaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}