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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39eca35a24fdc3e7012c4b4063dc2555a8aa500c0d2cbde235091af884740c05' 
  AND token = 'o6SPAL4yraTYDzKgVNIZl24G9reBKznz9KqIYduhsdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}