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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de6f498a07a68185e936acfdb929516ddad5a9f4bd40c567ba1719af9ae3c46b' 
  AND token = 'OrEwJDVMNP2d464UTp9Vd9b3nN0pihOf6cmns50WIwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}