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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c195bf217f2d82246a5269112e0df2242c84627d50819b2a59f4971f8d465405' 
  AND token = 'zE8TqWfnkGzRWoUNcK9qiqDf2siKKMFJFCUYxqF2Q+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}