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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef84bedd341017a6b537dc6040ece51b7358b115fb478e43293d55718ca6d0c2' 
  AND token = 'wJyRMuXxXEKWWI42DVlb6IYnNMkZN2uLaO5wKZnC+JE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}