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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d6bfcb3a660c0e7ffbc9ca261e2f782dd50e021f7112b36cfe469ad8da053b2' 
  AND token = 'T3IKMMpSfhdUG6sWuk5/QGlZ4wEnjFGSx0vZ1Br9gw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}