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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2f6a2805faf451532a6564777c02a375d42641ed9a47d1180c1e09699f7c2ec' 
  AND token = '2tffZhC2QEYJ48R09BuSGM2179gm5ReNQSCxm6+fxx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}