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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f21d4b9ae029c714809d91f56abb720aadf683624fc240b593f62e8b45f2684a' 
  AND token = 'adO3FyzPqGFWVooJVWxS8QPAgMcFggUWnFJdC5VRu0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}