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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ad37531cfab864cdb776cc29f8c996faddd2768232f80e0d2c91357340f57bb' 
  AND token = 'XpaTH2gxtwBvemhfsIClbcAw/u2+n4+yo7JOXk7XBng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}