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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b862f1a9260080f4878f99f0070be352bb4d50579522eee4fc50c04817f5a32e' 
  AND token = '3i+N0xe0i4Ch/AKmUsvbBuEZSpbaQcGd10uUVuowh9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}