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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '537eace5dcf7842dc9b4ad15e7a2726d95d0dc046effa87d6555ceaa99d29e97' 
  AND token = 'QasPF3SRjwWcrLeAz6kXsxyeq0qhBQSbeiS9298JOQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}