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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a5251bf02416f30a9aaf158d2de3c69f763602c8f013da2aaee13b1820f8adb' 
  AND token = 'ywxbvVQRgwbVznWeLDpyScoTW5xbcRBzeMBU1yld4zI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}